How to find tissue-specific transcription factor (TF) target genes?

Q&A: Coffee break with TRANSFAC

This event was held on May 21st, 2024

FREE online seminar

Seminar Description

In this webinar Prof. Dr. Alexander Kel will share with you the latest intriguing insights of gene regulation mechanisms. He will demonstrate how to perform tissue-specific gene regulation analysis and find enriched motifs using the TRANSFAC database and its MATCH Suite tool.

The following main questions will be in the focus of this seminar:

  • How to find tissue-specific TF target genes?
  • Why do you need TF binding sites?
  • Conserved TF binding sites – how important are they?
  • PWMs – is that all? What else?

Seminar Schedule

The session started on May 21 with a lecture from Prof. Dr. Alexander Kel (approx. 1 hour) and was continued with a Q&A session addressing the questions coming from the attendees of the online event (up to 30 minutes).

What You Get

  • 1 hour lecture on gene regulation analysis provided by one of the key opinion makers in this field
  • 30 minutes interactive Q&A session addressing your questions regarding search for TFBS
  • Time-unlimited access to the video record of the session

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The Lecturer

  • Alexander Kel received his Ph.D. in Bioinformatics, Molecular Biology and Genetics in 1990 and has has over 35 years of research experience in Bioinformatics
  • He studied at Novosibirsk State University, obtaining an M.S. in biology with a focus on mathematical biology in 1985
  • His work spans numerous bioinformatics branches (sequence analysis, gene recognition, promoter/enhancer analysis and prediction, prediction of RNA secondary structure, analysis of signal transduction pathways, identification of drug targets, systems biology and systems medicine)
  • He is the originator of the “fuzzy puzzle” concept for gene regulatory regions modeling
  • Developed “upstream analysis” for identifying biomarkers and drug targets in various diseases
  • Participated in over 20 national and international research projects
  • Author of more than 130 scientific publications and several book chapters on bioinformatics and systems biology
  • CEO and CSO of geneXplain GmbH, Wolfenbüttel, Germany
  • Visiting Professor at Royal College of Surgeons in Ireland (RCSI), Dublin, Ireland

Prerequisites

Basic knowledge of biochemistry and molecular biology. No programming skills are required.

To Whom It Might Be Interesting

  • Researchers interested in tissue-specific gene regulation principles
  • Bench biologists seeking for ways to deal with their sequencing data without any prior bioinformatics or coding experience

FAQ

That’s ok! All registered course attendees will receive access to the video record of the session together with the presentation materials. 

You can ask your questions live during the online event using the Q&A section of the online webinar, or you can send us your questions in advance using the form on this page and Prof. Dr. Alexander Kel will address them at the online event.

Sure! All licensed TRANSFAC users will be able to repeat all steps of the analysis that will be shown by Prof. Dr. Alexander Kel during the online event using their geneXplain platform and TRANSFAC accounts.

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