GENEXPLAIN RESEARCH
Research collaboration
As a highly active biomedical research company, geneXplain is proud to offer its expertise and products to all interested partners. You are welcome to invite us for collaboration in any of the applicable grant programs (we would act as a German SME partner) or include our software and databases in your grant applications for covering the license costs with the received funding.
COVID-19 RESEARCH
As a bioinformatics company we perform our own in silico research on COVID-19. We applied Genome Enhancer tool to publicly available COVID-19 datasets to identify prospective drug targets and treatments for this infection. The results of our studies were shared by geneXplain’s CSO Dr. Alexander Kel during our recent masterclasses, the video records of which are available below.
ChromRare
The ChromRare project focuses on understanding chromatinopathies (CPs), rare genetic diseases caused by mutations in chromatin regulators, by investigating their genetic and epigenetic determinants to develop new diagnostic and therapeutic strategies. The project aims to create disease models and identify disrupted regulatory pathways, addressing critical needs for understanding and treating CPs.Further details about the ChromRare project are available at the project homepage .
GlioResolve
The GLIORESOLVE project aims to develop new therapeutic strategies for glioblastoma (GBM), a highly aggressive brain tumor with a poor prognosis, by leveraging a novel tumor microenvironment (TME) classification system established in the Gliotrain Project. Key objectives include expanding immunotherapy options, optimizing pre-clinical models that mimic GBM TME subtypes, and testing new drug combinations tailored to these subtypes, all through a collaborative effort involving leading European researchers and advanced methodologies like multi-omics and computational modeling.
